Email this article Nucleation and Growth Modeling of Protein Crystals in Capillaries
- Authors: Sokolovskii A.S.1, Besedina N.A.2, Berdnikov Y.1, Dubrovskii V.G.1
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Affiliations:
- St. Petersburg National Research University of Information Technologies, Mechanics, and Optics
- St. Petersburg National Research Academic University, Russian Academy of Sciences
- Issue: Vol 52, No 16 (2018)
- Pages: 2132-2134
- Section: 26th INTERNATIONAL SYMPOSIUM “NANOSTRUCTURES: PHYSICS AND TECHNOLOGY”. NANOSTRUCTURE TECHNOLOGY
- URL: https://journals.rcsi.science/1063-7826/article/view/205485
- DOI: https://doi.org/10.1134/S1063782618160339
- ID: 205485
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Abstract
Within this work we model the spatial dependences of protein concentration, nucleation probability and the radius of lysozyme crystal in the experiments on capillary counter-diffusion crystallization. Within the model approach, we evaluate the conditions for the formation of lysozyme crystals with the target separation of 100 µm between centers of protein crystals. The predicted and observed number density, sizes and positions of protein crystals in capillary are in excellent agreement.
About the authors
A. S. Sokolovskii
St. Petersburg National Research University of Information Technologies, Mechanics, and Optics
Author for correspondence.
Email: sokolovskiy.a.s@niuitmo.ru
Russian Federation, St. Petersburg
N. A. Besedina
St. Petersburg National Research Academic University, Russian Academy of Sciences
Email: sokolovskiy.a.s@niuitmo.ru
Russian Federation, St. Petersburg
Yu. Berdnikov
St. Petersburg National Research University of Information Technologies, Mechanics, and Optics
Email: sokolovskiy.a.s@niuitmo.ru
Russian Federation, St. Petersburg
V. G. Dubrovskii
St. Petersburg National Research University of Information Technologies, Mechanics, and Optics
Email: sokolovskiy.a.s@niuitmo.ru
Russian Federation, St. Petersburg
