Applicability of the critical chromatography concept to proteomic problems. II. Effect of mobile phase on the separation of peptides and proteins taking into account the amino acid sequence
- 作者: Gorshkov A.1, Pridatchenko M.2, Perlova T.2, Tarasova I.2, Levitsky L.2, Gorshkov M.2, Evreinov V.1
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隶属关系:
- Semenov Institute of Chemical Physics, Russian Academy of Sciences
- Tal’rose Institute for Energy Problems of Chemical Physics
- 期: 卷 71, 编号 12 (2016)
- 页面: 1188-1197
- 栏目: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182195
- DOI: https://doi.org/10.1134/S106193481610004X
- ID: 182195
如何引用文章
详细
The effect of parameters of a binary mobile phase (chemical properties of components, gradient profile, flow rate, and pH) on the separation of peptides and proteins is theoretically investigated using a model of critical chromatography (model BioLCCC). It is demonstrated that the retention volume of peptides can be inverted by changing separation conditions.
作者简介
A. Gorshkov
Semenov Institute of Chemical Physics, Russian Academy of Sciences
Email: evreinov@polymer.chph.ras.ru
俄罗斯联邦, Moscow, 119991
M. Pridatchenko
Tal’rose Institute for Energy Problems of Chemical Physics
Email: evreinov@polymer.chph.ras.ru
俄罗斯联邦, Moscow, 119334
T. Perlova
Tal’rose Institute for Energy Problems of Chemical Physics
Email: evreinov@polymer.chph.ras.ru
俄罗斯联邦, Moscow, 119334
I. Tarasova
Tal’rose Institute for Energy Problems of Chemical Physics
Email: evreinov@polymer.chph.ras.ru
俄罗斯联邦, Moscow, 119334
L. Levitsky
Tal’rose Institute for Energy Problems of Chemical Physics
Email: evreinov@polymer.chph.ras.ru
俄罗斯联邦, Moscow, 119334
M. Gorshkov
Tal’rose Institute for Energy Problems of Chemical Physics
Email: evreinov@polymer.chph.ras.ru
俄罗斯联邦, Moscow, 119334
V. Evreinov
Semenov Institute of Chemical Physics, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: evreinov@polymer.chph.ras.ru
俄罗斯联邦, Moscow, 119991
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