Applicability of the critical chromatography concept to proteomic problems. II. Effect of mobile phase on the separation of peptides and proteins taking into account the amino acid sequence
- Авторлар: Gorshkov A.1, Pridatchenko M.2, Perlova T.2, Tarasova I.2, Levitsky L.2, Gorshkov M.2, Evreinov V.1
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Мекемелер:
- Semenov Institute of Chemical Physics, Russian Academy of Sciences
- Tal’rose Institute for Energy Problems of Chemical Physics
- Шығарылым: Том 71, № 12 (2016)
- Беттер: 1188-1197
- Бөлім: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182195
- DOI: https://doi.org/10.1134/S106193481610004X
- ID: 182195
Дәйексөз келтіру
Аннотация
The effect of parameters of a binary mobile phase (chemical properties of components, gradient profile, flow rate, and pH) on the separation of peptides and proteins is theoretically investigated using a model of critical chromatography (model BioLCCC). It is demonstrated that the retention volume of peptides can be inverted by changing separation conditions.
Авторлар туралы
A. Gorshkov
Semenov Institute of Chemical Physics, Russian Academy of Sciences
Email: evreinov@polymer.chph.ras.ru
Ресей, Moscow, 119991
M. Pridatchenko
Tal’rose Institute for Energy Problems of Chemical Physics
Email: evreinov@polymer.chph.ras.ru
Ресей, Moscow, 119334
T. Perlova
Tal’rose Institute for Energy Problems of Chemical Physics
Email: evreinov@polymer.chph.ras.ru
Ресей, Moscow, 119334
I. Tarasova
Tal’rose Institute for Energy Problems of Chemical Physics
Email: evreinov@polymer.chph.ras.ru
Ресей, Moscow, 119334
L. Levitsky
Tal’rose Institute for Energy Problems of Chemical Physics
Email: evreinov@polymer.chph.ras.ru
Ресей, Moscow, 119334
M. Gorshkov
Tal’rose Institute for Energy Problems of Chemical Physics
Email: evreinov@polymer.chph.ras.ru
Ресей, Moscow, 119334
V. Evreinov
Semenov Institute of Chemical Physics, Russian Academy of Sciences
Хат алмасуға жауапты Автор.
Email: evreinov@polymer.chph.ras.ru
Ресей, Moscow, 119991
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