Мақаланы E-mail арқылы жіберу Synthesis of Lutein and Astaxanthin Esters and Their In Silico Activity
- Авторлар: Pechinskii S.1, Kuregyan A.1, Oganesyan E.1, Stepanova E.1
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Мекемелер:
- Medical Pharmaceutical Institute of Pyatigorsk Branch of Volgograd Medical State University
- Шығарылым: Том 89, № 5 (2019)
- Беттер: 913-917
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222899
- DOI: https://doi.org/10.1134/S1070363219050098
- ID: 222899
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Аннотация
Esters of individual natural carotenoids lutein and astaxanthin with benzoic, 4-methylbenzoic, nicotinic, and mandelic acids have been synthesized. The esterification reaction of carotenoids has been carried out in an anhydrous medium at 37°C using of Novozyme 435 biocatalyst. The in silico prediction of the products activity by means of molecular docking has identified two compounds promising regarding the action towards the retinal protein Stard3 PDP code 5I9J.
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Авторлар туралы
S. Pechinskii
Medical Pharmaceutical Institute of Pyatigorsk Branch of Volgograd Medical State University
Хат алмасуға жауапты Автор.
Email: hplc@yandex.ru
Ресей, Pyatigorsk
A. Kuregyan
Medical Pharmaceutical Institute of Pyatigorsk Branch of Volgograd Medical State University
Email: hplc@yandex.ru
Ресей, Pyatigorsk
E. Oganesyan
Medical Pharmaceutical Institute of Pyatigorsk Branch of Volgograd Medical State University
Email: hplc@yandex.ru
Ресей, Pyatigorsk
E. Stepanova
Medical Pharmaceutical Institute of Pyatigorsk Branch of Volgograd Medical State University
Email: hplc@yandex.ru
Ресей, Pyatigorsk
