Synthesis of Lutein and Astaxanthin Esters and Their In Silico Activity
- 作者: Pechinskii S.1, Kuregyan A.1, Oganesyan E.1, Stepanova E.1
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隶属关系:
- Medical Pharmaceutical Institute of Pyatigorsk Branch of Volgograd Medical State University
- 期: 卷 89, 编号 5 (2019)
- 页面: 913-917
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222899
- DOI: https://doi.org/10.1134/S1070363219050098
- ID: 222899
如何引用文章
详细
Esters of individual natural carotenoids lutein and astaxanthin with benzoic, 4-methylbenzoic, nicotinic, and mandelic acids have been synthesized. The esterification reaction of carotenoids has been carried out in an anhydrous medium at 37°C using of Novozyme 435 biocatalyst. The in silico prediction of the products activity by means of molecular docking has identified two compounds promising regarding the action towards the retinal protein Stard3 PDP code 5I9J.
作者简介
S. Pechinskii
Medical Pharmaceutical Institute of Pyatigorsk Branch of Volgograd Medical State University
编辑信件的主要联系方式.
Email: hplc@yandex.ru
俄罗斯联邦, Pyatigorsk
A. Kuregyan
Medical Pharmaceutical Institute of Pyatigorsk Branch of Volgograd Medical State University
Email: hplc@yandex.ru
俄罗斯联邦, Pyatigorsk
E. Oganesyan
Medical Pharmaceutical Institute of Pyatigorsk Branch of Volgograd Medical State University
Email: hplc@yandex.ru
俄罗斯联邦, Pyatigorsk
E. Stepanova
Medical Pharmaceutical Institute of Pyatigorsk Branch of Volgograd Medical State University
Email: hplc@yandex.ru
俄罗斯联邦, Pyatigorsk
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