Vol 13, No 4 (2015)
- Year: 2015
- Articles: 15
- URL: https://journals.rcsi.science/ecolgenet/issue/view/134
- DOI: https://doi.org/10.17816/ecogen134
Articles
Assessment of morphometric indexes in the second generation of Scots pine trees in the Chernobyl exclusion zone
Abstract
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Molecular genetic analysis of the spread of resistance to organophosphate insecticides and pyrethroids in populations of the Colorado potato beetle in the Republic of Bashkortostan
Abstract
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Cytogenetic status in coal-miners with occupational pulmonary diseases and influence the polymorphisms of XpD and XpG genes
Abstract
Background. Coal-miners are exposed by various harmful factors (chemical agents, ionizing radiation, heavy metals, coal dust). Occupational pulmonary diseases may affect to the level of genotoxic damages. Materials and methods. Venous blood samples extracted from 90 coal-miners with various occupational pulmonary diseases and 26 healthy coal-miners (control 1). Blood samples obtained from 124 non-exposed men were used as the control 2. Assessment of cytogenetic damages was performed usingthe analysis of chromosome aberrations. PCR and gel electrophoresis were used to determine polymorphismsin the genes XpD(rs13181) and XpG(rs17655). Results. We found a significant increase in the frequency of the chromatid- and chromosome-type aberrations in coal-miners and the increase of the chromosomal interchange in miners with occupational pulmonary diseases. The modify effects of polymorphismsin the XpD and XpG genes to the level of chromosome aberrations were discovered. Conclusions. It was shown that the XpD and XpG genes can be used as potential molecular geneticmarkers of increased individual risk of occupational pulmonary diseases.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Pharmacologic correction of paclitaxel-induced geneand myelotoxicity with exstract of Scutellariae baicalensis hairy roots culture
Abstract
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Sup35 prionization [PSI+] influence the frequency of the gene and chromosome mutations, accounted in the alpha-test in yeast Saccharomyces cerevisiae
Abstract
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Peculiarities of negative consequences of mutagenic action
Abstract
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Genotoxic effect of fipronil on somatic and germ cells of mice
Abstract
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
The assessment of micronucleus frequency in lymphocytes in the cohort of coal-miners characterized by different polymorphisms of double strand break reparation genes
Abstract
Background: Coal-miners are exposed to a lot of number of harmful factors (chemical agents, ionizing radiation, heavy metals, coal dust etc.). Material and methods: Venous blood samples extracted from 129 coal-miners. Assessment of cytogenetic damage was performed using the cytokinesis-block micronucleus assay (CBMN) on peripheral blood lymphocytes. PCR and gel electrophoresis were used to determine polymorphisms in the genes Lig4 (rs1805388) and XRCC4 (rs6869366). Results: We found a significant increase in the frequency of binucleated lymphocytes with micronuclei (MN) and protrusions in carriers of the Ile/ Ile genotype of the Lig4 gene Thr9Ile polymorphism in comparison to Thr/Thr and Thr/Ile genotypes. Conclusions: Thr9Ile polymorphism within Lig4 gene can be used as potential molecular genetic markers of increased individual susceptibility to the complex of harmful factors in coal-mining conditions.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Markers of human extraembryonal cells individual radiosensitivity in vitro
Abstract
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
The genetics of the traits determining adaptability to abiotic stress in rice (Oryza sativa L.)
Abstract
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Genetic diversity comparative evaluation of Pinus Sylvestris L. and Picea x Fennica (regel) kom. native populations and clonal seed orchards in russian Karelia
Abstract
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Mitochondrial DNA d-loop polymorphism analysis for estimation of diversity in chicken flocks of Pavlov breed
Abstract
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Molecular phylogenetic analysis of the tonoplast H+-ATPase subunits
Abstract
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
The role of XRCC1, XRCC3 and PALB2 genes in the genesis of breast cancer
Abstract
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
High hydrostatic pressure influence on viability and mutagenesis of Salmonella Typhimurium
Abstract
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)