Synthesis and Cytotoxicity of 6-Substituted 1,4-Naphthoquinone Oxime Derivatives (II)
- 作者: Huang G.1, Zhao H.2, Li S.1
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隶属关系:
- School of Pharmacy
- School of Pharmaceutical Sciences and Chemistry
- 期: 卷 87, 编号 12 (2017)
- 页面: 2979-2985
- 栏目: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/221797
- DOI: https://doi.org/10.1134/S1070363217120416
- ID: 221797
如何引用文章
详细
In the present study, a series of 1,4-naphthoquinone oxime derivatives has been synthesized. The structures were confirmed by spectroscopic methods. The newly synthesized compounds were evaluated for their in vitro cytotoxicity. Among those, the compounds 8c, 8d, 8e, 12a, and 12b demonstrated potent cytotoxic activity comparable with that of the reference drug 5-Fu.
作者简介
G. Huang
School of Pharmacy
编辑信件的主要联系方式.
Email: guanghuangmedchem@hotmail.com
中国, Shanghai, 200240
H. Zhao
School of Pharmaceutical Sciences and Chemistry
Email: ssli@sjtu.edu.cn
中国, Dali, 671000
S. Li
School of Pharmacy
编辑信件的主要联系方式.
Email: ssli@sjtu.edu.cn
中国, Shanghai, 200240
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