Enviar artigo por via de e-mail Synthesis and Cytotoxicity of 6-Substituted 1,4-Naphthoquinone Oxime Derivatives (II)
- Autores: Huang G.1, Zhao H.2, Li S.1
-
Afiliações:
- School of Pharmacy
- School of Pharmaceutical Sciences and Chemistry
- Edição: Volume 87, Nº 12 (2017)
- Páginas: 2979-2985
- Seção: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/221797
- DOI: https://doi.org/10.1134/S1070363217120416
- ID: 221797
Citar
Acesso aberto
Acesso está concedido
Somente assinantes
Resumo
In the present study, a series of 1,4-naphthoquinone oxime derivatives has been synthesized. The structures were confirmed by spectroscopic methods. The newly synthesized compounds were evaluated for their in vitro cytotoxicity. Among those, the compounds 8c, 8d, 8e, 12a, and 12b demonstrated potent cytotoxic activity comparable with that of the reference drug 5-Fu.
Palavras-chave
Sobre autores
G. Huang
School of Pharmacy
Autor responsável pela correspondência
Email: guanghuangmedchem@hotmail.com
República Popular da China, Shanghai, 200240
H. Zhao
School of Pharmaceutical Sciences and Chemistry
Email: ssli@sjtu.edu.cn
República Popular da China, Dali, 671000
S. Li
School of Pharmacy
Autor responsável pela correspondência
Email: ssli@sjtu.edu.cn
República Popular da China, Shanghai, 200240
