Synthesis and Cytotoxicity of 6-Substituted 1,4-Naphthoquinone Oxime Derivatives (II)
- Авторлар: Huang G.1, Zhao H.2, Li S.1
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Мекемелер:
- School of Pharmacy
- School of Pharmaceutical Sciences and Chemistry
- Шығарылым: Том 87, № 12 (2017)
- Беттер: 2979-2985
- Бөлім: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/221797
- DOI: https://doi.org/10.1134/S1070363217120416
- ID: 221797
Дәйексөз келтіру
Аннотация
In the present study, a series of 1,4-naphthoquinone oxime derivatives has been synthesized. The structures were confirmed by spectroscopic methods. The newly synthesized compounds were evaluated for their in vitro cytotoxicity. Among those, the compounds 8c, 8d, 8e, 12a, and 12b demonstrated potent cytotoxic activity comparable with that of the reference drug 5-Fu.
Негізгі сөздер
Авторлар туралы
G. Huang
School of Pharmacy
Хат алмасуға жауапты Автор.
Email: guanghuangmedchem@hotmail.com
ҚХР, Shanghai, 200240
H. Zhao
School of Pharmaceutical Sciences and Chemistry
Email: ssli@sjtu.edu.cn
ҚХР, Dali, 671000
S. Li
School of Pharmacy
Хат алмасуға жауапты Автор.
Email: ssli@sjtu.edu.cn
ҚХР, Shanghai, 200240
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