Synthesis of N-vinylpyrrolidone copolymers with 2-aminoethyl methacrylate as drug carriers
- 作者: Solovskii M.1, Borisenko M.1, Ershov A.1, Zakharova N.1, Tarabukina E.1
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隶属关系:
- Institute of Macromolecular Compounds
- 期: 卷 87, 编号 2 (2017)
- 页面: 276-281
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/218344
- DOI: https://doi.org/10.1134/S1070363217020207
- ID: 218344
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详细
Radical copolymerization of N-vinylpyrrolidone and 2-aminoethyl methacrylate hydrochloride has been studied. Molecular and hydrodynamic characteristics of the resulting copolymers have been determined, and their structure has been confirmed. Conditions favoring conversion of these copolymers into copolymers of N-vinylpyrrolidone with 2-aminoethyl methacrylate of different composition have been elucidated. The suitability of the prepared copolymers as polymeric carriers of monofluoroquinolone ofloxacin has been demonstrated.
作者简介
M. Solovskii
Institute of Macromolecular Compounds
Email: aarghm@yandex.ru
俄罗斯联邦, Bol’shoi pr. 31, St. Petersburg, 199004
M. Borisenko
Institute of Macromolecular Compounds
编辑信件的主要联系方式.
Email: aarghm@yandex.ru
俄罗斯联邦, Bol’shoi pr. 31, St. Petersburg, 199004
A. Ershov
Institute of Macromolecular Compounds
Email: aarghm@yandex.ru
俄罗斯联邦, Bol’shoi pr. 31, St. Petersburg, 199004
N. Zakharova
Institute of Macromolecular Compounds
Email: aarghm@yandex.ru
俄罗斯联邦, Bol’shoi pr. 31, St. Petersburg, 199004
E. Tarabukina
Institute of Macromolecular Compounds
Email: aarghm@yandex.ru
俄罗斯联邦, Bol’shoi pr. 31, St. Petersburg, 199004
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