Synthesis of N-vinylpyrrolidone copolymers with 2-aminoethyl methacrylate as drug carriers
- Autores: Solovskii M.1, Borisenko M.1, Ershov A.1, Zakharova N.1, Tarabukina E.1
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Afiliações:
- Institute of Macromolecular Compounds
- Edição: Volume 87, Nº 2 (2017)
- Páginas: 276-281
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/218344
- DOI: https://doi.org/10.1134/S1070363217020207
- ID: 218344
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Resumo
Radical copolymerization of N-vinylpyrrolidone and 2-aminoethyl methacrylate hydrochloride has been studied. Molecular and hydrodynamic characteristics of the resulting copolymers have been determined, and their structure has been confirmed. Conditions favoring conversion of these copolymers into copolymers of N-vinylpyrrolidone with 2-aminoethyl methacrylate of different composition have been elucidated. The suitability of the prepared copolymers as polymeric carriers of monofluoroquinolone ofloxacin has been demonstrated.
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Sobre autores
M. Solovskii
Institute of Macromolecular Compounds
Email: aarghm@yandex.ru
Rússia, Bol’shoi pr. 31, St. Petersburg, 199004
M. Borisenko
Institute of Macromolecular Compounds
Autor responsável pela correspondência
Email: aarghm@yandex.ru
Rússia, Bol’shoi pr. 31, St. Petersburg, 199004
A. Ershov
Institute of Macromolecular Compounds
Email: aarghm@yandex.ru
Rússia, Bol’shoi pr. 31, St. Petersburg, 199004
N. Zakharova
Institute of Macromolecular Compounds
Email: aarghm@yandex.ru
Rússia, Bol’shoi pr. 31, St. Petersburg, 199004
E. Tarabukina
Institute of Macromolecular Compounds
Email: aarghm@yandex.ru
Rússia, Bol’shoi pr. 31, St. Petersburg, 199004