Synthesis of N-vinylpyrrolidone copolymers with 2-aminoethyl methacrylate as drug carriers
- Авторлар: Solovskii M.1, Borisenko M.1, Ershov A.1, Zakharova N.1, Tarabukina E.1
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Мекемелер:
- Institute of Macromolecular Compounds
- Шығарылым: Том 87, № 2 (2017)
- Беттер: 276-281
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/218344
- DOI: https://doi.org/10.1134/S1070363217020207
- ID: 218344
Дәйексөз келтіру
Аннотация
Radical copolymerization of N-vinylpyrrolidone and 2-aminoethyl methacrylate hydrochloride has been studied. Molecular and hydrodynamic characteristics of the resulting copolymers have been determined, and their structure has been confirmed. Conditions favoring conversion of these copolymers into copolymers of N-vinylpyrrolidone with 2-aminoethyl methacrylate of different composition have been elucidated. The suitability of the prepared copolymers as polymeric carriers of monofluoroquinolone ofloxacin has been demonstrated.
Негізгі сөздер
Авторлар туралы
M. Solovskii
Institute of Macromolecular Compounds
Email: aarghm@yandex.ru
Ресей, Bol’shoi pr. 31, St. Petersburg, 199004
M. Borisenko
Institute of Macromolecular Compounds
Хат алмасуға жауапты Автор.
Email: aarghm@yandex.ru
Ресей, Bol’shoi pr. 31, St. Petersburg, 199004
A. Ershov
Institute of Macromolecular Compounds
Email: aarghm@yandex.ru
Ресей, Bol’shoi pr. 31, St. Petersburg, 199004
N. Zakharova
Institute of Macromolecular Compounds
Email: aarghm@yandex.ru
Ресей, Bol’shoi pr. 31, St. Petersburg, 199004
E. Tarabukina
Institute of Macromolecular Compounds
Email: aarghm@yandex.ru
Ресей, Bol’shoi pr. 31, St. Petersburg, 199004