![Открытый доступ](https://journals.rcsi.science/lib/pkp/templates/images/icons/text_open.png)
![Доступ закрыт](https://journals.rcsi.science/lib/pkp/templates/images/icons/text_unlock.png)
![Доступ закрыт](https://journals.rcsi.science/lib/pkp/templates/images/icons/text_lock.png)
Том 88, № 1 (2018)
- Год: 2018
- Статей: 28
- URL: https://journals.rcsi.science/1070-3632/issue/view/13693
Article
Solubility of d-Element Salts in Organic and Aqueous–Organic Solvents: VI.1 Structure and Thermal Stability of Cadmium Iodide and Bromide Solvates with Dimethylacetamide and Dimethylformamide
Аннотация
Five solvates, [CdBr2(DMF)]n, [CdBr2(DMA)]n, [CdI2(DMF)]n, [Cd(DMF)6][Cd2I6], and {[Cd(DMA)6][Cd5I12]n}m, were isolated from the ternary systems CdX2–L–H2O (X = Br, I; L = N,N-dimethylacetamide, N,N-dimethylformamide) and characterized by the X-ray single crystal analysis. The structures of the first three solvates is similar to each other in structures and represent a one-dimensional polymer chain, the fourth solvate has the discrete structure containing [Cd(DMF)6]2+ and [Cd2I6]2– ions, and the fifth solvate contains discrete [Cd(DMA)6]2+ cations and the polymer anionic fragment [Cd5I12]n2n–.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Chromato–Mass Spectrometric Identification of Unusual Products of 4-Isopropylphenol Oxidation in Aqueous Solutions
Аннотация
4-Isopropylphenol has been chosen as the simplest object to model the processes of oxidation of organic compounds with air oxygen in aqueous media, since it contains a hydrogen atom at the tertiary carbon atom in the α-position with benzene ring and a hydroxyl group enabling mass-spectrometric detection of the products in the negative ions mode. It has been stated that oxidation of 4-isopropylphenol with air oxygen in aqueous media becomes noticeable as the solution pH approaches the рKа value of the substrate (10.25). The major product [4-isopropyl-2-(4-isopropylphenoxy)phenol] is formed via nucleophilic addition of the starting 4-isopropylphenol at the intermediate product of its oxidation, quinone methide. Intensity of electrochemical oxidation can be tubed by changing the electrode potential. The highest conversion of 4-isopropylphenol has been observed at potential 1.5–3.0 V, the formed compounds being the products of transformation of the same quinone methide intermediate. The obtained data have explained the formation and diversity of dimeric and oligomeric products of oxidation of natural flavonoids.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Methylation of Aliphatic and Aromatic Carboxylic Acids with Dimethyl Carbonate under the Influence of Manganese and Iron Carbonyls
Аннотация
The synthesis of methyl esters has been carried out via the reaction of aliphatic and aromatic carboxylic acids with dimethyl carbonate in the presence of manganese and iron carbonyls. The optimal ratio of catalyst and reagents and other conditions for the synthesis of methyl esters of carboxylic acids with high yield have been found.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Colloid and Nanosized Catalysts in Organic Synthesis: XIX.1 Influence of the Support Nature on Hydrogenation Catalysis of Cyclic Olefins by Nickel Nanoparticles
Аннотация
Gas-phase hydrogenation of cycloalkenes in the presence of nickel nanoparticles supported on Ceokar-2, BAU-A activated carbon, alumina, and NaX zeolite proceeds at 140–240°C and atmospheric pressure of hydrogen. The conversion and selectivity depend on the type of support and on the hydrogen excess.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Hydrosilylation of Allyl Ethers in the Presence of Supported Sulfur-Containing Platinum(II) Complexes
Аннотация
Hydrosilylation of allyl ethyl, allyl butyl, allyl glycidyl, allyl benzyl, and allyl phenyl ethers by 1,1,3,3-tetramethyldisiloxane in the presence of supported sulfur-containing platinum(II) complexes with the general formula [{SiO2}O2Si(Me)(CH2)3SR]2PtCl2 (R = Bu, Hex, Bn; {SiO2} is silica surface) and side processes have been studied.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Synthesis and Structure of Geminally Activated 1-Nitro-4-phenylbuta-1,3-dienes
Аннотация
The condensation of cinnamaldehyde with nitro-substituted CH acids (ethyl nitroacetate, nitroacetone, nitroacetophenone, and nitroacetonitrile) afforded a series of geminally activated 1-nitro-4-phenylbuta- 1,3-dienes. Their structure was determined on the basis of a set of 1H, 13C–{1H}, 15N NMR, and IR spectra.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Azomethines Based on Pyridoxal-Derived Aromatic Aldehydes
Аннотация
The reaction of pyridoxal with 2,4-dihydroxybenzaldehyde in a hydrochloric acid solution gave 1-(5-formyl-2,4-dihydroxyphenyl)-7-hydroxy-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-5-ium chloride. Treatment of the latter with sodium hydride in ethanol afforded a free aldehyde in 85% yield. A series of azomethines and imidazolidines was obtained by reacting the obtained aldehyde with various amines and diamines.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
A Study on Hydrolytic Stability of Isatin N-Mannich Bases
Аннотация
Stability parameters of biologically active compounds with N-Mannich base motif in their structure, which is susceptible to hydrolysis, have been studied. A procedure for the synthesis of small molecule compounds reactivating the function of the p53 tumor suppressor protein was developed, and the dependence of the Mannich base degradation rate on the structure of the compounds was established. For the hydrolysis reaction we determined the rate constants and calculated ρ, ΔG#, ΔH, and ΔS. Modifications of active compounds that retain the activity at the maximum possible stability were proposed.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Isatin Derivatives Containing Sterically Hindered Phenolic Fragment and Water-Soluble Acyl Hydrazones on Their Basis: Synthesis and Antimicrobial Activity
Аннотация
Condensation reactions of isatin derivatives with 3,5-di(tert-butyl)-4-hydroxybenzyl acetate and the Girard’s reagent T has afforded a series of novel water-soluble isatin-3-acyl hydrazones containing a sterically hindered phenolic fragment in position 1 of the heterocycle; antimicrobial activity of the products has been estimated. It has been shown that the isatin derivatives with bromine or methoxy substituent in the benzo fragment as well as the acyl hydrazones containing 5-methyl or 5-ethyl group are the most active against Staphylococcus aureus and Bacillus cereus.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Synthesis and Antioxidant Activity of Sterically Hindered Phenol Derivatives of Carboxy- and Sulfobetaines
Аннотация
New multifunctional antioxidants based on carboxy- and sulfobetaines with sterically hindered phenol fragments were synthesized. The antioxidant capacity of the compounds determined in the reactions of their oxidation by electrogenerated bromine is comparable to that of ascorbic acid and ionol.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Unexpected Reaction of Ethyl 4-(Chloromethyl)pyrazolo- [5,1-c][1,2,4]triazine-3-carboxylates with Thiourea and Its Mechanism
Аннотация
The reaction of ethyl 4-(chloromethyl)pyrazolo[5,1-c][1,2,4]triazine-3-carboxylates with thiourea in dimethylformamide involves ANRORC rearrangement (Addition of the Nucleophile, Ring Opening, and Ring Closure) followed by N-formylation to give N-{5-(4-oxo-8-phenyl-1,4-dihydropyrazolo[5,1-c][1,2,4]-triazin-3-yl)-1,3-triazol-2-yl}formamides whose structure was confirmed by X-ray analysis. The reaction mechanism has been studied by HPLC/MS.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Reactivity of α-Amino Acids in the Reaction with Esters in Aqueous–1,4-Dioxane Media
Аннотация
The kinetics of the reaction of a series of α-amino acids with 4-nitrophenyl acetate, 4-nitrophenyl benzoate, and 2,4,6-trinitrophenyl benzoate in aqueous 1,4-dioxane medium has been studied. Kinetics of the reactions involving 4-nitrophenyl acetate and 2,4,6-trinitrophenyl benzoate has complied with the Brønsted dependence and revealed linear correlation between rate constant logarithm and the energy difference of the frontier orbitals of α-amino acids anions.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Macroheterocyclic Compounds with Thiadiazole Fragments. Synthesis and Properties
Аннотация
The reactions of 1-imino-2-phenyl-1H-inden-3-amine with 3,5-diamino-1,2,4- and 2,5-diamino-1,3,4- thiadiazoles were used to synthesize linear 1: 2 and 2: 1 condensation products, as well as symmetrical macroheterocyclic compounds. The synthesized compounds were characterized by IR, UV, and 1Н NMR spectroscopy.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Reactions of Unsaturated Ketones with Bis(trimethylsilyl) Hypophosphite
Аннотация
Bis(trimethylsilyl) hypophosphite reacts with unsaturated ketones (methyl vinyl ketone and mesityl oxide) to give, depending on the reaction conditions, 1: 1 or 1: 2 adducts after hydrolysis. It was found that the intramolecular cyclization of the 1: 2 reaction product with mesityl oxide, trimethylsilyl bis(2-methyl-4- oxopentan-2-yl)phosphinate, yields, after hydrolysis, a phosphorinane with exocyclic carbonyl and hydroxyl groups.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Mechanism of Protodephenylation of 1,3-Silaheterocyclohexanes. Effect of Heteroatom
Аннотация
The mechanism of electrophilic cleavage of the Si–Ph bond in 1,3-silaheterocyclohexanes is investigated. 3-Aryl-3-silatetrahydropyrans are shown to be less prone to the cleavage of the Si–Ph bond under the action of trifluromethanesulfonic acid than the corresponding 3-silathianes or silacyclohexanes. The effect of heteroatom (N, O, S) in the ring on the functionalization at the silicon atom in 1,3-silaheterocyclohexanes was studied experimentally by the method of NMR spectroscopy and theoretically by DFT calculations and the mechanism was suggested of dephenylation as a function of the nature of heteroatom.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Condensation Products of D-Ribose with Thiol-Containing Hydrazides and Gold Glyconanoparticles Thereof
Аннотация
The accessible D-ribose mercaptoacetyl-, 3-mercaptopropionyl-, and 2-mercaprobenzoylhydrazones were used to develop a method of synthesis of gold glyconanoparticles with the average particle diameter of 10–40 nm and a low polydispersity index.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Synthesis of Silver Glyconanoparticles Based on 3-Thiopropionylhydrazones of Mono- and Disaccharides
Аннотация
A method of synthesis of silver glyconanoparticles with average particle size 15–40 nm and low polydispersity index based on available 3-thiopropionylhydrazones of mono- and disaccharides has been elaborated. The prepared compounds have exhibited high antifungal, antibacterial, and antiviral activity and are promising for further comprehensive study.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Influence of Synthesis Conditions on the Morphology and Spectral-Luminescent Properties of Films of Organic-Inorganic Perovskite CH3NH3PbI2.98Cl0.02
Аннотация
The influence of the synthesis conditions (rotation speed used for spin-coating deposition of the film, film drying temperature, and the ratio of the PbI2 and CH3NH3I reactants in solutions) on the microstructure, phase composition, and spectral-luminescent properties of films of organic-inorganic perovskite CH3NH3PbI3–xClx (x = 0, 0.02) was elucidated.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Membrane Extraction of Lithium and Sodium Ions with 2-Ethylhexyl Hydrogen [Bis(2-ethylhexyl)amino]methylphosphonate
Аннотация
Lithium and sodium ion transport through membranes impregnated with a solution of 2-ethylhexyl hydrogen [bis(2-ethylhexyl)amino]methylphosphonate in kerosene has been studied. Factors determining the efficiency and selectivity of membrane extraction have been determined. Introduction of neutral aminomethylphosphine oxide into the membrane phase has been shown to enhance the selectivity for lithium ions.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Letters to the Editor
Features of Reactions of Some 1-Arylaminomethylisatins with Girard’s Reagent T
Аннотация
Depending on the structure of the substituent at the endocyclic nitrogen atom, the reactions of aminomethylisatins with the Girard’s reagent T can proceed both with the elimination of the aminomethyl group and with its retention resulting in the formation of the corresponding positively charged isatin-3-acylhydrazones.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Synthesis of 2,3-Dihydro[1,4]oxazino[2,3,4-ij]quinolinium Bromide and Its Reaction with Sodium Hydroxide
Аннотация
The reaction of quinolin-8-ol with 1,2-dibromoethane in dimethylformamide gave 2,3-dihydro[1,4]-oxazino[2,3,4-ij]quinolinium bromide which reacted with aqueous sodium hydroxide to afford 2,3,4,5-tetrahydro[1,4]oxazino[2,3,4-ij]quinoline, 2,3,4,5-tetrahydro[1,4]oxazino[2,3,4-ij]quinolin-5-ol, and 2,3,4,5-tetrahydro[1,4]oxazino[2,3,4-ij]quinolin-5-one.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Reaction of 4-Chloro-6-[1-(vinylsulfonyl)pyrrolidin-2-yl]benzene-1,3-diol with Some Amines
Аннотация
4-Chloro-6-[1-(vinylsulfonyl)pyrrolidin-2-yl]benzene-1,3-diol prepared by the reaction of 2-ethoxypyrrolidine with 4-chlororesorcinol was introduced into the aza-Michael reaction with various amines which led to the formation of new 1-sulfonyl-2-arylpyrrolidines
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Synthesis of Methyl-Substituted Derivatives of 5-Hydroxy-6-methyluracil
Аннотация
5-Hydroxy-3,6-dimethyluracil, 5-methoxy-1,3,6-trimethyluracil, earlier unknown 5-methoxy-6- methyluracil, 5-methoxy-1,6-dimethyluracil, and 5-methoxy-3,6-dimethyluracil have been synthesized via alkylation of 5-hydroxy-6-methyluracil with dimethylsulfate in aqueous-alkaline media. The obtained compounds have been identified using 1Н, 13С, and 15N NMR spectroscopy.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Phosphorylation of Oxyethylated Calix[4]resorcinols with Phosphorous Acid Amides
Аннотация
The reaction of octa-2-hydroxyethylated calix[4]resorcinols with phosphorous acid amides and the subsequent thionylation by elemental sulfur afforded hydrolytically stable oxyethyl calix[4]resorcinols containing eight thiophosphoryl fragments.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Synthesis and Some Reactions of New Acetals Containing Aminoethylenephosphoryl Fragment
Аннотация
Phosphonoethylated amino acetals were synthesized for the first time by reacting vinylphosphonates with α- and γ-aminoacetals. The reaction of 2-methylresorcinol with the acetals in ethanol in the presence of hydrochloric acid afforded the first representative of diarylbutylamines containing β-aminoethylenephosphoryl fragment.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Synthesis of 2-Naphthylacetylene Selenides from 4-(2-Naphthyl)-1,2,3-selenadiazole
Аннотация
4-(2-Naphthyl)-1,2,3-selenadiazole under the action of bases eagerly decomposes with liberation of nitrogen to form potassium 2-(2-naphthyl)ethyneselenolate. By further treatment of the reaction mixture with the excess of alkyl halide the corresponding methyl- and butyl-2-(2-naphthyl)-1-ethynyl selenides were obtained. In the absence of alkyl halides treating with the potassium hydroxide ethanol solution yields 4-(2- naphthyl)-2-[1-(2-naphthyl)-2-[1-(2-naphthyl)methylidenee]-1,3-diselenol.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)
Synthesis and Structure of a Copper(II) Complex of N,N'-Bis(di-para-tolylphosphinoylmethyl)-1,8-diamino- 3,6-dioxaoctane
Аннотация
A copper(II) complex of N,N'-bis(di-para-tolylphosphinoylmethyl)-1,8-diamino-3,6-dioxaoctane was synthesized and its crystal structure was established. The inner coordination sphere of the complex is a strongly distorted trigonal bipyramid. Coordination involves the phosphoryl oxygen atoms, nitrogen atoms, and ether oxygen atom, and one axial position is occupied by a water molecule.
![pages](/img/style/pages.png)
![views](/img/style/views.png)
![](/img/style/loadingSmall.gif)