Email this article Synthesis and Anticancer Activity of 1,2,4-Oxadiazol Linked Benzimidazole Derivatives
- Authors: Srinivas M.1, Satyaveni S.1, Ram B.2
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Affiliations:
- Department of Chemistry
- Green Evolution Laboratories
- Issue: Vol 88, No 12 (2018)
- Pages: 2653-2657
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222611
- DOI: https://doi.org/10.1134/S1070363218120289
- ID: 222611
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Abstract
A new series of 1,2,4-oxadiazole linked benzimidazole derivatives 11a–11j are synthesized. Their structures are confirmed by 1H and 13C NMR and mass spectral data. The products are tested for their anticancer activity against three human cancer cell lines, MCF-7 (breast), A549 (lung), and A375 (melanoma). The compounds 11b, 11c, 11g, and 11h are determined to be more potent than the control (MCF-7).
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About the authors
M. Srinivas
Department of Chemistry
Email: msrinivaschem1@gmail.com
India, Kakinada, 533003
S. Satyaveni
Department of Chemistry
Author for correspondence.
Email: msrinivaschem1@gmail.com
India, Kakinada, 533003
B. Ram
Green Evolution Laboratories
Email: msrinivaschem1@gmail.com
India, Wangapally Village, Nalgonda, AP, 508 286
