Synthesis and Anticancer Activity of 1,2,4-Oxadiazol Linked Benzimidazole Derivatives
- Авторлар: Srinivas M.1, Satyaveni S.1, Ram B.2
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Мекемелер:
- Department of Chemistry
- Green Evolution Laboratories
- Шығарылым: Том 88, № 12 (2018)
- Беттер: 2653-2657
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222611
- DOI: https://doi.org/10.1134/S1070363218120289
- ID: 222611
Дәйексөз келтіру
Аннотация
A new series of 1,2,4-oxadiazole linked benzimidazole derivatives 11a–11j are synthesized. Their structures are confirmed by 1H and 13C NMR and mass spectral data. The products are tested for their anticancer activity against three human cancer cell lines, MCF-7 (breast), A549 (lung), and A375 (melanoma). The compounds 11b, 11c, 11g, and 11h are determined to be more potent than the control (MCF-7).
Негізгі сөздер
Авторлар туралы
M. Srinivas
Department of Chemistry
Email: msrinivaschem1@gmail.com
Үндістан, Kakinada, 533003
S. Satyaveni
Department of Chemistry
Хат алмасуға жауапты Автор.
Email: msrinivaschem1@gmail.com
Үндістан, Kakinada, 533003
B. Ram
Green Evolution Laboratories
Email: msrinivaschem1@gmail.com
Үндістан, Wangapally Village, Nalgonda, AP, 508 286