Отправить статью по E-mail Synthesis and Anticancer Activity of 1,2,4-Oxadiazol Linked Benzimidazole Derivatives
- Авторы: Srinivas M.1, Satyaveni S.1, Ram B.2
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Учреждения:
- Department of Chemistry
- Green Evolution Laboratories
- Выпуск: Том 88, № 12 (2018)
- Страницы: 2653-2657
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222611
- DOI: https://doi.org/10.1134/S1070363218120289
- ID: 222611
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Аннотация
A new series of 1,2,4-oxadiazole linked benzimidazole derivatives 11a–11j are synthesized. Their structures are confirmed by 1H and 13C NMR and mass spectral data. The products are tested for their anticancer activity against three human cancer cell lines, MCF-7 (breast), A549 (lung), and A375 (melanoma). The compounds 11b, 11c, 11g, and 11h are determined to be more potent than the control (MCF-7).
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Об авторах
M. Srinivas
Department of Chemistry
Email: msrinivaschem1@gmail.com
Индия, Kakinada, 533003
S. Satyaveni
Department of Chemistry
Автор, ответственный за переписку.
Email: msrinivaschem1@gmail.com
Индия, Kakinada, 533003
B. Ram
Green Evolution Laboratories
Email: msrinivaschem1@gmail.com
Индия, Wangapally Village, Nalgonda, AP, 508 286
