Synthesis and Biological Activity of β-Aminoketones, Secondary Aminopropanols and Oximes of 2-Aminothiophene Series
- 作者: Gevorgyan G.1, Hakobyan N.1, Hovakimyan S.1, Melkonyan A.1, Panosyan G.1
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隶属关系:
- Scientific and Technological Center of Organic and Pharmaceutical Chemistry
- 期: 卷 89, 编号 11 (2019)
- 页面: 2328-2332
- 栏目: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/223182
- DOI: https://doi.org/10.1134/S1070363219110264
- ID: 223182
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详细
The reactions of substituted 3-dietliylaminopropan-1-ones hydrochlorides with 2-amino-6-(H, alkyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitriles and ethyl 2-amino-6-(H, methyl)-4,5,6,7-tetrariydrobenzo[b]-thiophene-3-carboxylate furnished β-aminoketones of 2-aminothiophene series. The latter were converted into the corresponding secondary aminopropanols and oximes. Antioxidant activity of synthesized compounds and effect on some parameters of the blood coagulation system were investigated.
作者简介
G. Gevorgyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
编辑信件的主要联系方式.
Email: gyulgev@gmail.com
亚美尼亚, Yerevan, 0014
N. Hakobyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
亚美尼亚, Yerevan, 0014
S. Hovakimyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
亚美尼亚, Yerevan, 0014
A. Melkonyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
亚美尼亚, Yerevan, 0014
G. Panosyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
亚美尼亚, Yerevan, 0014