Synthesis and Biological Activity of β-Aminoketones, Secondary Aminopropanols and Oximes of 2-Aminothiophene Series
- Авторлар: Gevorgyan G.1, Hakobyan N.1, Hovakimyan S.1, Melkonyan A.1, Panosyan G.1
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Мекемелер:
- Scientific and Technological Center of Organic and Pharmaceutical Chemistry
- Шығарылым: Том 89, № 11 (2019)
- Беттер: 2328-2332
- Бөлім: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/223182
- DOI: https://doi.org/10.1134/S1070363219110264
- ID: 223182
Дәйексөз келтіру
Аннотация
The reactions of substituted 3-dietliylaminopropan-1-ones hydrochlorides with 2-amino-6-(H, alkyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitriles and ethyl 2-amino-6-(H, methyl)-4,5,6,7-tetrariydrobenzo[b]-thiophene-3-carboxylate furnished β-aminoketones of 2-aminothiophene series. The latter were converted into the corresponding secondary aminopropanols and oximes. Antioxidant activity of synthesized compounds and effect on some parameters of the blood coagulation system were investigated.
Негізгі сөздер
Авторлар туралы
G. Gevorgyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Хат алмасуға жауапты Автор.
Email: gyulgev@gmail.com
Армения, Yerevan, 0014
N. Hakobyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
Армения, Yerevan, 0014
S. Hovakimyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
Армения, Yerevan, 0014
A. Melkonyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
Армения, Yerevan, 0014
G. Panosyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
Армения, Yerevan, 0014