Synthesis and Biological Activity of β-Aminoketones, Secondary Aminopropanols and Oximes of 2-Aminothiophene Series
- Авторы: Gevorgyan G.1, Hakobyan N.1, Hovakimyan S.1, Melkonyan A.1, Panosyan G.1
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Учреждения:
- Scientific and Technological Center of Organic and Pharmaceutical Chemistry
- Выпуск: Том 89, № 11 (2019)
- Страницы: 2328-2332
- Раздел: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/223182
- DOI: https://doi.org/10.1134/S1070363219110264
- ID: 223182
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Аннотация
The reactions of substituted 3-dietliylaminopropan-1-ones hydrochlorides with 2-amino-6-(H, alkyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitriles and ethyl 2-amino-6-(H, methyl)-4,5,6,7-tetrariydrobenzo[b]-thiophene-3-carboxylate furnished β-aminoketones of 2-aminothiophene series. The latter were converted into the corresponding secondary aminopropanols and oximes. Antioxidant activity of synthesized compounds and effect on some parameters of the blood coagulation system were investigated.
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Об авторах
G. Gevorgyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Автор, ответственный за переписку.
Email: gyulgev@gmail.com
Армения, Yerevan, 0014
N. Hakobyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
Армения, Yerevan, 0014
S. Hovakimyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
Армения, Yerevan, 0014
A. Melkonyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
Армения, Yerevan, 0014
G. Panosyan
Scientific and Technological Center of Organic and Pharmaceutical Chemistry
Email: gyulgev@gmail.com
Армения, Yerevan, 0014