Synthesis of Biaryl Derivatives of Spirofurochromanone in Water and Their Anticancer Activity


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Biaryl derivatives of spirofurochromanones have been synthesised from 4-bromophenyl derivatives of spirofurochromanones upon catalysis by Pd/C in water. Structures of the synthesised compounds are derived from IR, NMR and HRMS spectral data. The compounds have been tested for in vitro cytotoxicity supported by docking studies.

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D. Ashok

Green and Medicinal Chemistry Lab, Department of Chemistry

编辑信件的主要联系方式.
Email: ashokdou@gmail.com
印度, Hyderabad, Telangana, 500007

E. Madhuri

Green and Medicinal Chemistry Lab, Department of Chemistry; Department of Chemistry

Email: ashokdou@gmail.com
印度, Hyderabad, Telangana, 500007; Nizamabad, Telangana, 5033443

M. Sarasija

Department of Chemistry

Email: ashokdou@gmail.com
印度, Karimnagar, Telangana, 505001

S. Sree Kanth

Molecular Modeling and Medicinal Chemistry Group, Department of Chemistry, University, College of Science; Department of Chemistry, Nizam College

Email: ashokdou@gmail.com
印度, Hyderabad, Telangana, 500007; Hyderabad, Telangana, 500001

M. Vijjulatha

Molecular Modeling and Medicinal Chemistry Group, Department of Chemistry, University, College of Science

Email: ashokdou@gmail.com
印度, Hyderabad, Telangana, 500007

Akkiraju Gayatri

Department of Genetics, Drug Design and Molecular Medicine Lab

Email: ashokdou@gmail.com
印度, Hyderabad, Telangana, 500007

Someswar Sagurthi

Department of Genetics, Drug Design and Molecular Medicine Lab

Email: ashokdou@gmail.com
印度, Hyderabad, Telangana, 500007

N. Krishna

Analytical Division

Email: ashokdou@gmail.com
印度, Hyderabad, Telangana, 500007


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