Enviar artigo por via de e-mail Synthesis of Biaryl Derivatives of Spirofurochromanone in Water and Their Anticancer Activity
- Autores: Ashok D.1, Madhuri E.1,2, Sarasija M.2, Sree Kanth S.3,4, Vijjulatha M.3, Gayatri A.5, Sagurthi S.5, Krishna N.6
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Afiliações:
- Green and Medicinal Chemistry Lab, Department of Chemistry
- Department of Chemistry
- Molecular Modeling and Medicinal Chemistry Group, Department of Chemistry, University, College of Science
- Department of Chemistry, Nizam College
- Department of Genetics, Drug Design and Molecular Medicine Lab
- Analytical Division
- Edição: Volume 89, Nº 10 (2019)
- Páginas: 2129-2135
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/223129
- DOI: https://doi.org/10.1134/S1070363219100220
- ID: 223129
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Resumo
Biaryl derivatives of spirofurochromanones have been synthesised from 4-bromophenyl derivatives of spirofurochromanones upon catalysis by Pd/C in water. Structures of the synthesised compounds are derived from IR, NMR and HRMS spectral data. The compounds have been tested for in vitro cytotoxicity supported by docking studies.
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Sobre autores
D. Ashok
Green and Medicinal Chemistry Lab, Department of Chemistry
Autor responsável pela correspondência
Email: ashokdou@gmail.com
Índia, Hyderabad, Telangana, 500007
E. Madhuri
Green and Medicinal Chemistry Lab, Department of Chemistry; Department of Chemistry
Email: ashokdou@gmail.com
Índia, Hyderabad, Telangana, 500007; Nizamabad, Telangana, 5033443
M. Sarasija
Department of Chemistry
Email: ashokdou@gmail.com
Índia, Karimnagar, Telangana, 505001
S. Sree Kanth
Molecular Modeling and Medicinal Chemistry Group, Department of Chemistry, University, College of Science; Department of Chemistry, Nizam College
Email: ashokdou@gmail.com
Índia, Hyderabad, Telangana, 500007; Hyderabad, Telangana, 500001
M. Vijjulatha
Molecular Modeling and Medicinal Chemistry Group, Department of Chemistry, University, College of Science
Email: ashokdou@gmail.com
Índia, Hyderabad, Telangana, 500007
Akkiraju Gayatri
Department of Genetics, Drug Design and Molecular Medicine Lab
Email: ashokdou@gmail.com
Índia, Hyderabad, Telangana, 500007
Someswar Sagurthi
Department of Genetics, Drug Design and Molecular Medicine Lab
Email: ashokdou@gmail.com
Índia, Hyderabad, Telangana, 500007
N. Krishna
Analytical Division
Email: ashokdou@gmail.com
Índia, Hyderabad, Telangana, 500007
