Design, Synthesis and Anticancer Activity of 1,2,4-Thiadiazole Derivatives Bearing 1,2,4-Oxadiazole
- 作者: Sudhakar D.1,2, Rao A.1, Reddy C.2
-
隶属关系:
- Medicinal Chemistry Division
- Department of Chemistry
- 期: 卷 89, 编号 8 (2019)
- 页面: 1696-1701
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/223048
- DOI: https://doi.org/10.1134/S1070363219080243
- ID: 223048
如何引用文章
详细
A series of novel 1,2,4-thiadiazole derivatives bearing 1,2,4-oxadiazole is synthesized. Structures of the synthesized compounds are confirmed by 1H and 13C NMR, and mass spectra. All products are evaluated for their anticancer activity towards human cancer cell lines: MCF-7 (breast), A549 (lung), Colo-205 (colon), and A2780 (ovarian), and demonstrate good to moderate anticancer activity. Four synthesized compounds are characterised by potent activity.
作者简介
D. Sudhakar
Medicinal Chemistry Division; Department of Chemistry
编辑信件的主要联系方式.
Email: sudhakardgs1org@outlook.com
印度, 28A, Nacharam, IDA-Mallapur, Hyderabad, Telangana, 500076; Hyderabad, Telangana, 500085
A. Rao
Medicinal Chemistry Division
Email: sudhakardgs1org@outlook.com
印度, 28A, Nacharam, IDA-Mallapur, Hyderabad, Telangana, 500076
Ch. Reddy
Department of Chemistry
Email: sudhakardgs1org@outlook.com
印度, Hyderabad, Telangana, 500085