Мақаланы E-mail арқылы жіберу Design, Synthesis and Anticancer Activity of 1,2,4-Thiadiazole Derivatives Bearing 1,2,4-Oxadiazole
- Авторлар: Sudhakar D.1,2, Rao A.1, Reddy C.2
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Мекемелер:
- Medicinal Chemistry Division
- Department of Chemistry
- Шығарылым: Том 89, № 8 (2019)
- Беттер: 1696-1701
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/223048
- DOI: https://doi.org/10.1134/S1070363219080243
- ID: 223048
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Аннотация
A series of novel 1,2,4-thiadiazole derivatives bearing 1,2,4-oxadiazole is synthesized. Structures of the synthesized compounds are confirmed by 1H and 13C NMR, and mass spectra. All products are evaluated for their anticancer activity towards human cancer cell lines: MCF-7 (breast), A549 (lung), Colo-205 (colon), and A2780 (ovarian), and demonstrate good to moderate anticancer activity. Four synthesized compounds are characterised by potent activity.
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Авторлар туралы
D. Sudhakar
Medicinal Chemistry Division; Department of Chemistry
Хат алмасуға жауапты Автор.
Email: sudhakardgs1org@outlook.com
Үндістан, 28A, Nacharam, IDA-Mallapur, Hyderabad, Telangana, 500076; Hyderabad, Telangana, 500085
A. Rao
Medicinal Chemistry Division
Email: sudhakardgs1org@outlook.com
Үндістан, 28A, Nacharam, IDA-Mallapur, Hyderabad, Telangana, 500076
Ch. Reddy
Department of Chemistry
Email: sudhakardgs1org@outlook.com
Үндістан, Hyderabad, Telangana, 500085
