An Efficient Synthesis and Antimicrobial Activity of 5-{2-[(1-Aryl-1H-1,2,3-triazol-4-yl)methoxy]-5-bromophenyl}isoxazoles
- 作者: Thotla K.1, Giri Noole V.1, Kedika B.1, Reddy K.1
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隶属关系:
- Department of Chemistry
- 期: 卷 89, 编号 4 (2019)
- 页面: 789-793
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222872
- DOI: https://doi.org/10.1134/S1070363219040248
- ID: 222872
如何引用文章
详细
A novel series of 1,2,3-triazolyl isoxazole derivatives is synthesized from the corresponding propargylated isoxazoles and a number of aryl azides by the Click reaction. The highest yields of the reaction are achieved in the presence of copper sulphate pentahydrate and sodium ascorbate, and using DMF:water (2:1) as a medium. The compounds structures are elucidated from various spectral data. Antimicrobial activity tests of the title compounds demonstrate their moderate to good results compared to the standard.
作者简介
K. Thotla
Department of Chemistry
Email: krreddych@gmail.com
印度, Hyderabad, 500007
V. Giri Noole
Department of Chemistry
Email: krreddych@gmail.com
印度, Hyderabad, 500007
B. Kedika
Department of Chemistry
Email: krreddych@gmail.com
印度, Hyderabad, 500007
K. Reddy
Department of Chemistry
编辑信件的主要联系方式.
Email: krreddych@gmail.com
印度, Hyderabad, 500007