An Efficient Synthesis and Antimicrobial Activity of 5-{2-[(1-Aryl-1H-1,2,3-triazol-4-yl)methoxy]-5-bromophenyl}isoxazoles
- Авторлар: Thotla K.1, Giri Noole V.1, Kedika B.1, Reddy K.1
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Мекемелер:
- Department of Chemistry
- Шығарылым: Том 89, № 4 (2019)
- Беттер: 789-793
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222872
- DOI: https://doi.org/10.1134/S1070363219040248
- ID: 222872
Дәйексөз келтіру
Аннотация
A novel series of 1,2,3-triazolyl isoxazole derivatives is synthesized from the corresponding propargylated isoxazoles and a number of aryl azides by the Click reaction. The highest yields of the reaction are achieved in the presence of copper sulphate pentahydrate and sodium ascorbate, and using DMF:water (2:1) as a medium. The compounds structures are elucidated from various spectral data. Antimicrobial activity tests of the title compounds demonstrate their moderate to good results compared to the standard.
Авторлар туралы
K. Thotla
Department of Chemistry
Email: krreddych@gmail.com
Үндістан, Hyderabad, 500007
V. Giri Noole
Department of Chemistry
Email: krreddych@gmail.com
Үндістан, Hyderabad, 500007
B. Kedika
Department of Chemistry
Email: krreddych@gmail.com
Үндістан, Hyderabad, 500007
K. Reddy
Department of Chemistry
Хат алмасуға жауапты Автор.
Email: krreddych@gmail.com
Үндістан, Hyderabad, 500007