Reaction of diphenylphosphinoylallene derivatives of cytisine
- 作者: Brel’ V.1, Kovaleva E.1, Enchev D.2
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隶属关系:
- Nesmeyanov Institute of Organoelement Compounds
- Konstantin Preslavsky University of Shumen
- 期: 卷 87, 编号 8 (2017)
- 页面: 1731-1736
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/220988
- DOI: https://doi.org/10.1134/S1070363217080163
- ID: 220988
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详细
Diphenylphosphinoylallenes containing a ClCH2 group were synthesized, and their reaction with cytisine was studied. It was shown that the reaction involves exclusives as nucleophilic substitution of chlorine in the chloromethyl group. The synthesized conjugates of cytisine with diphenylphosphinoylallene derivatives are of interest as potential agonists of nicotinic acetylcholine neuroreceptors (nAChRs).
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作者简介
V. Brel’
Nesmeyanov Institute of Organoelement Compounds
编辑信件的主要联系方式.
Email: v_brel@mail.ru
俄罗斯联邦, ul. Vavilova 28, Moscow, 119991
E. Kovaleva
Nesmeyanov Institute of Organoelement Compounds
Email: v_brel@mail.ru
俄罗斯联邦, ul. Vavilova 28, Moscow, 119991
D. Enchev
Konstantin Preslavsky University of Shumen
Email: v_brel@mail.ru
保加利亚, Shumen
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