Reaction of diphenylphosphinoylallene derivatives of cytisine
- Авторы: Brel’ V.1, Kovaleva E.1, Enchev D.2
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Учреждения:
- Nesmeyanov Institute of Organoelement Compounds
- Konstantin Preslavsky University of Shumen
- Выпуск: Том 87, № 8 (2017)
- Страницы: 1731-1736
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/220988
- DOI: https://doi.org/10.1134/S1070363217080163
- ID: 220988
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Аннотация
Diphenylphosphinoylallenes containing a ClCH2 group were synthesized, and their reaction with cytisine was studied. It was shown that the reaction involves exclusives as nucleophilic substitution of chlorine in the chloromethyl group. The synthesized conjugates of cytisine with diphenylphosphinoylallene derivatives are of interest as potential agonists of nicotinic acetylcholine neuroreceptors (nAChRs).
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Об авторах
V. Brel’
Nesmeyanov Institute of Organoelement Compounds
Автор, ответственный за переписку.
Email: v_brel@mail.ru
Россия, ul. Vavilova 28, Moscow, 119991
E. Kovaleva
Nesmeyanov Institute of Organoelement Compounds
Email: v_brel@mail.ru
Россия, ul. Vavilova 28, Moscow, 119991
D. Enchev
Konstantin Preslavsky University of Shumen
Email: v_brel@mail.ru
Болгария, Shumen
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