Synthesis, characterisation, and antibacterial activity of some novel vanillin related hydrazone derivatives bearing 1,2,3-triazole ring
- 作者: Kiran K.1,2, Ashok D.3, Rao B.3, Sarasija M.1, Rao A.4
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隶属关系:
- Department of Chemistry
- Green Evolution Laboratories
- Green and Medicinal Chemistry Laboratory, Department of Chemistry
- Vagdevi Innoscience Pvt. Ltd
- 期: 卷 87, 编号 6 (2017)
- 页面: 1288-1294
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/220374
- DOI: https://doi.org/10.1134/S1070363217060251
- ID: 220374
如何引用文章
详细
Vanillin, hydrazone and 1,2,3-triazole containing functional groups derivatives demonstrate antibacterial activity. In the present work, we present synthesis of eight new vanillin related hydrazone derivatives bearing 1,2,3-triazole ring skeleton 9a–9e, 10a–10e obtained with high yields by the coupling of aldehydes 6 and 7 with substituted benzohydrazides 8a–8e in ethanol. IR, NMR and MS data and elemental analysis confirm the structures of products. All title compounds were evaluated in vitro for their antibacterial activity against a panel of Gram positive and Gram negative bacteria and compounds 9d and 10d exhibited high activity.
作者简介
K. Kiran
Department of Chemistry; Green Evolution Laboratories
Email: ashokdou@gmail.com
印度, Hyderabad, Telangana, 500085; Nalgonda, Telangana, 00085
D. Ashok
Green and Medicinal Chemistry Laboratory, Department of Chemistry
编辑信件的主要联系方式.
Email: ashokdou@gmail.com
印度, Hyderabad, Telangana, 500085
B. Rao
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
印度, Hyderabad, Telangana, 500085
M. Sarasija
Department of Chemistry
Email: ashokdou@gmail.com
印度, Karimnagar, Telangana, 505001
A. Rao
Vagdevi Innoscience Pvt. Ltd
Email: ashokdou@gmail.com
印度, Nacharam, Hyderabad, Telangana, 500085