Enantioselective synthesis of (S)-1-phenylethanol, a precursor to low-molecular-weight bioregulators
- 作者: Chanysheva A.1, Yunusova G.1, Vorobyova T.1, Zorin V.1
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隶属关系:
- Ufa State Petroleum Technological University
- 期: 卷 86, 编号 13 (2016)
- 页面: 3021-3024
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/217752
- DOI: https://doi.org/10.1134/S107036321613017X
- ID: 217752
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详细
A procedure has been proposed for the synthesis of (S)-(–)-1-phenylethanol, an important building block for the preparation of medicinal agents possessing antidiabetic, antidepressant, and antirabic activity, as well as of antifeedants and antiparasitic, antimicrobial, and antifungal metabolites, by enantioselective bioreduction of acetophenone. Different exogenous reducing agents (propan-2-ol, ethanol, and glucose) were tried to improve the yield of the target product and its enantiomeric purity.
作者简介
A. Chanysheva
Ufa State Petroleum Technological University
编辑信件的主要联系方式.
Email: aliyach@mail.ru
俄罗斯联邦, ul. Kosmonavtov 1, Bashkortostan, Ufa, 450062
G. Yunusova
Ufa State Petroleum Technological University
Email: aliyach@mail.ru
俄罗斯联邦, ul. Kosmonavtov 1, Bashkortostan, Ufa, 450062
T. Vorobyova
Ufa State Petroleum Technological University
Email: aliyach@mail.ru
俄罗斯联邦, ul. Kosmonavtov 1, Bashkortostan, Ufa, 450062
V. Zorin
Ufa State Petroleum Technological University
Email: aliyach@mail.ru
俄罗斯联邦, ul. Kosmonavtov 1, Bashkortostan, Ufa, 450062