Enantioselective synthesis of (S)-1-phenylethanol, a precursor to low-molecular-weight bioregulators
- Авторлар: Chanysheva A.1, Yunusova G.1, Vorobyova T.1, Zorin V.1
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Мекемелер:
- Ufa State Petroleum Technological University
- Шығарылым: Том 86, № 13 (2016)
- Беттер: 3021-3024
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/217752
- DOI: https://doi.org/10.1134/S107036321613017X
- ID: 217752
Дәйексөз келтіру
Аннотация
A procedure has been proposed for the synthesis of (S)-(–)-1-phenylethanol, an important building block for the preparation of medicinal agents possessing antidiabetic, antidepressant, and antirabic activity, as well as of antifeedants and antiparasitic, antimicrobial, and antifungal metabolites, by enantioselective bioreduction of acetophenone. Different exogenous reducing agents (propan-2-ol, ethanol, and glucose) were tried to improve the yield of the target product and its enantiomeric purity.
Авторлар туралы
A. Chanysheva
Ufa State Petroleum Technological University
Хат алмасуға жауапты Автор.
Email: aliyach@mail.ru
Ресей, ul. Kosmonavtov 1, Bashkortostan, Ufa, 450062
G. Yunusova
Ufa State Petroleum Technological University
Email: aliyach@mail.ru
Ресей, ul. Kosmonavtov 1, Bashkortostan, Ufa, 450062
T. Vorobyova
Ufa State Petroleum Technological University
Email: aliyach@mail.ru
Ресей, ul. Kosmonavtov 1, Bashkortostan, Ufa, 450062
V. Zorin
Ufa State Petroleum Technological University
Email: aliyach@mail.ru
Ресей, ul. Kosmonavtov 1, Bashkortostan, Ufa, 450062
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