Green synthesis and antibacterial evaluation of some new 1-aryl-3-(1-aryl-1H-[1,2,3]triazol-4-yl)-propenones
- 作者: Linga Goud G.1, Ramesh S.1, Ashok D.1, Prabhakar Reddy V.1
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隶属关系:
- Green and Medicinal Chemistry Lab, Department of Chemistry
- 期: 卷 86, 编号 6 (2016)
- 页面: 1419-1423
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215437
- DOI: https://doi.org/10.1134/S1070363216060293
- ID: 215437
如何引用文章
详细
A new series of 1-aryl-3-(1-aryl-1H-[1,2,3]triazol-4-yl)propenones (6a–6j) was synthesized by condensation of substituted acetophenones (5a–5c) with substituted 1-aryl-1H-[1,2,3]triazole-4-carbaldehydes (4a–4d) in the presence of potassium hydroxide under conditions of grinding and microwave irradiation. All the newly synthesized compounds were characterized by the IR, NMR, and mass spectroscopic analyses and their antibacterial activity against gram-positive and gram-negative bacterial strains was evaluated. Among the compounds synthesized, better activity was exhibited by 6a, 6c, 6f, 6g, and 6i.
作者简介
G. Linga Goud
Green and Medicinal Chemistry Lab, Department of Chemistry
编辑信件的主要联系方式.
Email: lingamgudikadi@gmail.com
印度, Hyderabad, 500007
S. Ramesh
Green and Medicinal Chemistry Lab, Department of Chemistry
Email: lingamgudikadi@gmail.com
印度, Hyderabad, 500007
D. Ashok
Green and Medicinal Chemistry Lab, Department of Chemistry
Email: lingamgudikadi@gmail.com
印度, Hyderabad, 500007
V. Prabhakar Reddy
Green and Medicinal Chemistry Lab, Department of Chemistry
Email: lingamgudikadi@gmail.com
印度, Hyderabad, 500007