Green synthesis and antibacterial evaluation of some new 1-aryl-3-(1-aryl-1H-[1,2,3]triazol-4-yl)-propenones
- Авторлар: Linga Goud G.1, Ramesh S.1, Ashok D.1, Prabhakar Reddy V.1
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Мекемелер:
- Green and Medicinal Chemistry Lab, Department of Chemistry
- Шығарылым: Том 86, № 6 (2016)
- Беттер: 1419-1423
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215437
- DOI: https://doi.org/10.1134/S1070363216060293
- ID: 215437
Дәйексөз келтіру
Аннотация
A new series of 1-aryl-3-(1-aryl-1H-[1,2,3]triazol-4-yl)propenones (6a–6j) was synthesized by condensation of substituted acetophenones (5a–5c) with substituted 1-aryl-1H-[1,2,3]triazole-4-carbaldehydes (4a–4d) in the presence of potassium hydroxide under conditions of grinding and microwave irradiation. All the newly synthesized compounds were characterized by the IR, NMR, and mass spectroscopic analyses and their antibacterial activity against gram-positive and gram-negative bacterial strains was evaluated. Among the compounds synthesized, better activity was exhibited by 6a, 6c, 6f, 6g, and 6i.
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Авторлар туралы
G. Linga Goud
Green and Medicinal Chemistry Lab, Department of Chemistry
Хат алмасуға жауапты Автор.
Email: lingamgudikadi@gmail.com
Үндістан, Hyderabad, 500007
S. Ramesh
Green and Medicinal Chemistry Lab, Department of Chemistry
Email: lingamgudikadi@gmail.com
Үндістан, Hyderabad, 500007
D. Ashok
Green and Medicinal Chemistry Lab, Department of Chemistry
Email: lingamgudikadi@gmail.com
Үндістан, Hyderabad, 500007
V. Prabhakar Reddy
Green and Medicinal Chemistry Lab, Department of Chemistry
Email: lingamgudikadi@gmail.com
Үндістан, Hyderabad, 500007