Green synthesis and antibacterial evaluation of some new 1-aryl-3-(1-aryl-1H-[1,2,3]triazol-4-yl)-propenones
- Авторы: Linga Goud G.1, Ramesh S.1, Ashok D.1, Prabhakar Reddy V.1
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Учреждения:
- Green and Medicinal Chemistry Lab, Department of Chemistry
- Выпуск: Том 86, № 6 (2016)
- Страницы: 1419-1423
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215437
- DOI: https://doi.org/10.1134/S1070363216060293
- ID: 215437
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Аннотация
A new series of 1-aryl-3-(1-aryl-1H-[1,2,3]triazol-4-yl)propenones (6a–6j) was synthesized by condensation of substituted acetophenones (5a–5c) with substituted 1-aryl-1H-[1,2,3]triazole-4-carbaldehydes (4a–4d) in the presence of potassium hydroxide under conditions of grinding and microwave irradiation. All the newly synthesized compounds were characterized by the IR, NMR, and mass spectroscopic analyses and their antibacterial activity against gram-positive and gram-negative bacterial strains was evaluated. Among the compounds synthesized, better activity was exhibited by 6a, 6c, 6f, 6g, and 6i.
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Об авторах
G. Linga Goud
Green and Medicinal Chemistry Lab, Department of Chemistry
Автор, ответственный за переписку.
Email: lingamgudikadi@gmail.com
Индия, Hyderabad, 500007
S. Ramesh
Green and Medicinal Chemistry Lab, Department of Chemistry
Email: lingamgudikadi@gmail.com
Индия, Hyderabad, 500007
D. Ashok
Green and Medicinal Chemistry Lab, Department of Chemistry
Email: lingamgudikadi@gmail.com
Индия, Hyderabad, 500007
V. Prabhakar Reddy
Green and Medicinal Chemistry Lab, Department of Chemistry
Email: lingamgudikadi@gmail.com
Индия, Hyderabad, 500007