Reaction of diphenylphosphinoylallene derivatives of cytisine
- Autores: Brel’ V.1, Kovaleva E.1, Enchev D.2
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Afiliações:
- Nesmeyanov Institute of Organoelement Compounds
- Konstantin Preslavsky University of Shumen
- Edição: Volume 87, Nº 8 (2017)
- Páginas: 1731-1736
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/220988
- DOI: https://doi.org/10.1134/S1070363217080163
- ID: 220988
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Resumo
Diphenylphosphinoylallenes containing a ClCH2 group were synthesized, and their reaction with cytisine was studied. It was shown that the reaction involves exclusives as nucleophilic substitution of chlorine in the chloromethyl group. The synthesized conjugates of cytisine with diphenylphosphinoylallene derivatives are of interest as potential agonists of nicotinic acetylcholine neuroreceptors (nAChRs).
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Sobre autores
V. Brel’
Nesmeyanov Institute of Organoelement Compounds
Autor responsável pela correspondência
Email: v_brel@mail.ru
Rússia, ul. Vavilova 28, Moscow, 119991
E. Kovaleva
Nesmeyanov Institute of Organoelement Compounds
Email: v_brel@mail.ru
Rússia, ul. Vavilova 28, Moscow, 119991
D. Enchev
Konstantin Preslavsky University of Shumen
Email: v_brel@mail.ru
Bulgária, Shumen
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