Functionalization of 2-Phosphoryl-Substituted Phenols

Resumo

The nitration, bromination, diazo coupling, sulfonation, and alkylation of the aromatic ring of a series of 2-phosphoryl-substituted phenols have been studied for the first time. 2,6-Diphosphorylphenols have been obtained for the first time via 1,3-phosphorotropic phosphate-phosphonate rearrangement. The alkylation of 2-(diphenylphosphoryl)phenol at the hydroxy group with 2-bromo- and 2-chloroethanols has been studied under conventional heating and microwave irradiation conditions.