An Efficient Microwave Assisted Synthesis and Antimicrobial Activty of 1,2,3-Triazolyl-pyrrolidinyl-quinolinolines
- Autores: Pradeep M.1, Vishnuvardhan M.1, Bala Krishna V.1, Madhusudhan Raju R.1
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Afiliações:
- Department of Chemistry
- Edição: Volume 89, Nº 2 (2019)
- Páginas: 313-318
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222762
- DOI: https://doi.org/10.1134/S1070363219020233
- ID: 222762
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Resumo
A novel series of 1,2,3-triazolyl-pyrrolidinyl-quinolinolines are synthesised by the Click reaction of alkynes with aromatic azides catalysed by CuI under microwave assisted and conventional conditions. All synthesized 1,2,3-triazoles are screened for their in vitro antimicrobial activity against different bacterial and fungal pathogens. Majority of the synthesized compounds demonstrate moderate to good inhibition zones compared to the standard drugs.
Sobre autores
M. Pradeep
Department of Chemistry
Email: pradeep.marampally@gmail.com
Índia, Hyderabad, Telangana, 500007
M. Vishnuvardhan
Department of Chemistry
Email: pradeep.marampally@gmail.com
Índia, Hyderabad, Telangana, 500007
V. Bala Krishna
Department of Chemistry
Email: pradeep.marampally@gmail.com
Índia, Hyderabad, Telangana, 500007
R. Madhusudhan Raju
Department of Chemistry
Autor responsável pela correspondência
Email: pradeep.marampally@gmail.com
Índia, Hyderabad, Telangana, 500007
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