An Efficient Microwave Assisted Synthesis and Antimicrobial Activty of 1,2,3-Triazolyl-pyrrolidinyl-quinolinolines
- Authors: Pradeep M.1, Vishnuvardhan M.1, Bala Krishna V.1, Madhusudhan Raju R.1
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Affiliations:
- Department of Chemistry
- Issue: Vol 89, No 2 (2019)
- Pages: 313-318
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222762
- DOI: https://doi.org/10.1134/S1070363219020233
- ID: 222762
Cite item
Abstract
A novel series of 1,2,3-triazolyl-pyrrolidinyl-quinolinolines are synthesised by the Click reaction of alkynes with aromatic azides catalysed by CuI under microwave assisted and conventional conditions. All synthesized 1,2,3-triazoles are screened for their in vitro antimicrobial activity against different bacterial and fungal pathogens. Majority of the synthesized compounds demonstrate moderate to good inhibition zones compared to the standard drugs.
About the authors
M. Pradeep
Department of Chemistry
Email: pradeep.marampally@gmail.com
India, Hyderabad, Telangana, 500007
M. Vishnuvardhan
Department of Chemistry
Email: pradeep.marampally@gmail.com
India, Hyderabad, Telangana, 500007
V. Bala Krishna
Department of Chemistry
Email: pradeep.marampally@gmail.com
India, Hyderabad, Telangana, 500007
R. Madhusudhan Raju
Department of Chemistry
Author for correspondence.
Email: pradeep.marampally@gmail.com
India, Hyderabad, Telangana, 500007
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