An Efficient Microwave Assisted Synthesis and Antimicrobial Activty of 1,2,3-Triazolyl-pyrrolidinyl-quinolinolines

Аннотация

A novel series of 1,2,3-triazolyl-pyrrolidinyl-quinolinolines are synthesised by the Click reaction of alkynes with aromatic azides catalysed by CuI under microwave assisted and conventional conditions. All synthesized 1,2,3-triazoles are screened for their in vitro antimicrobial activity against different bacterial and fungal pathogens. Majority of the synthesized compounds demonstrate moderate to good inhibition zones compared to the standard drugs.