Biological evaluations and spectroscopic characterizations of 3-(4-ethoxyphenyl)-2-methylacrylate based organotin(IV) carboxylates derivatives
- Autores: Tariq M.1,2, Sirajuddin M.2, Ali S.2, Khalid N.3, Shah N.4
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Afiliações:
- Institute of Chemical Sciences
- Department of Chemistry
- Chemistry Division
- Department of Biosciences
- Edição: Volume 87, Nº 11 (2017)
- Páginas: 2690-2698
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221626
- DOI: https://doi.org/10.1134/S1070363217110263
- ID: 221626
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Resumo
Six new organotin(IV) carboxylates, [Me2SnL2] (1), [n-Bu2SnL2] (2), [n-Oct2SnL2] (3), [Me3SnL] (4), [n-Bu3SnL] (5) and [Ph3SnL] (6), where L = 3-(4-ethoxyphenyl)-2-methylacrylate, have been synthesized and characterized by FT-IR, NMR spectroscopy and elemental analyses. The synthesized compounds were tested for in vitro antibacterial and antifungal activities. The complexes 4–6 demonstrated higher activity than the complexes 1–3. UV-Vis absorption spectroscopy indicated that the ligand and its complexes interacted with DNA via partial intercalation as well as minor groove binding.
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Sobre autores
M. Tariq
Institute of Chemical Sciences; Department of Chemistry
Autor responsável pela correspondência
Email: mtnazir@yahoo.com
Paquistão, Multan, 60000; Islamabad, 45320
M. Sirajuddin
Department of Chemistry
Email: mtnazir@yahoo.com
Paquistão, Bannu, 28100
S. Ali
Department of Chemistry
Email: mtnazir@yahoo.com
Paquistão, Islamabad, 45320
N. Khalid
Chemistry Division
Email: mtnazir@yahoo.com
Paquistão, Islamabad
N. Shah
Department of Biosciences
Email: mtnazir@yahoo.com
Paquistão, Islamabad