Biological evaluations and spectroscopic characterizations of 3-(4-ethoxyphenyl)-2-methylacrylate based organotin(IV) carboxylates derivatives
- Авторлар: Tariq M.1,2, Sirajuddin M.2, Ali S.2, Khalid N.3, Shah N.4
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Мекемелер:
- Institute of Chemical Sciences
- Department of Chemistry
- Chemistry Division
- Department of Biosciences
- Шығарылым: Том 87, № 11 (2017)
- Беттер: 2690-2698
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221626
- DOI: https://doi.org/10.1134/S1070363217110263
- ID: 221626
Дәйексөз келтіру
Аннотация
Six new organotin(IV) carboxylates, [Me2SnL2] (1), [n-Bu2SnL2] (2), [n-Oct2SnL2] (3), [Me3SnL] (4), [n-Bu3SnL] (5) and [Ph3SnL] (6), where L = 3-(4-ethoxyphenyl)-2-methylacrylate, have been synthesized and characterized by FT-IR, NMR spectroscopy and elemental analyses. The synthesized compounds were tested for in vitro antibacterial and antifungal activities. The complexes 4–6 demonstrated higher activity than the complexes 1–3. UV-Vis absorption spectroscopy indicated that the ligand and its complexes interacted with DNA via partial intercalation as well as minor groove binding.
Негізгі сөздер
Авторлар туралы
M. Tariq
Institute of Chemical Sciences; Department of Chemistry
Хат алмасуға жауапты Автор.
Email: mtnazir@yahoo.com
Пәкістан, Multan, 60000; Islamabad, 45320
M. Sirajuddin
Department of Chemistry
Email: mtnazir@yahoo.com
Пәкістан, Bannu, 28100
S. Ali
Department of Chemistry
Email: mtnazir@yahoo.com
Пәкістан, Islamabad, 45320
N. Khalid
Chemistry Division
Email: mtnazir@yahoo.com
Пәкістан, Islamabad
N. Shah
Department of Biosciences
Email: mtnazir@yahoo.com
Пәкістан, Islamabad