Enviar artigo por via de e-mail Synthesis of tetrahydroisoquinoline derivatives and evaluation of their anti-breast cancer activity
- Autores: Zhang X.1, Yu F.2, Ding X.1, He X.1, Zou D.1
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Afiliações:
- Department of Breast Tumor Surgery
- Department of Medical Record Management
- Edição: Volume 86, Nº 6 (2016)
- Páginas: 1430-1433
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215464
- DOI: https://doi.org/10.1134/S1070363216060311
- ID: 215464
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Resumo
Four novel tetrahydroisoquinoline derivatives 1–4 were synthesized and characterized by IR, 1H NMR, HRMS, and single crystal X-ray crystallography. Anticancer effect of the products were studied on five human breast cancer cell lines including MDA-MB-231, MDA-MB-468, SK-BR-3, MCF7, HCC70 T4-2. Compounds 3 and 4 demonstrated higher activity than 1 and 2.
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Sobre autores
X. Zhang
Department of Breast Tumor Surgery
Email: zoude_hong66@163.com
República Popular da China, Hangzhou, Zhejiang, 310022
F. Yu
Department of Medical Record Management
Email: zoude_hong66@163.com
República Popular da China, Hangzhou, Zhejiang, 310022
X. Ding
Department of Breast Tumor Surgery
Email: zoude_hong66@163.com
República Popular da China, Hangzhou, Zhejiang, 310022
X. He
Department of Breast Tumor Surgery
Email: zoude_hong66@163.com
República Popular da China, Hangzhou, Zhejiang, 310022
D. Zou
Department of Breast Tumor Surgery
Autor responsável pela correspondência
Email: zoude_hong66@163.com
República Popular da China, Hangzhou, Zhejiang, 310022
