Мақаланы E-mail арқылы жіберу Synthesis and Antibacterial Assay of Some New Pyrenyl Pyridine Candidates
- Авторлар: Khalifa N.M.1,2, Haiba M.E.2, Taha M.M.3, Al-Omar M.A.1
-
Мекемелер:
- Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy
- Therapeutic Chemistry Department, Pharmaceutical and Drug Industries Division
- Department of Chemistry, Faculty of Science
- Шығарылым: Том 89, № 2 (2019)
- Беттер: 319-323
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222764
- DOI: https://doi.org/10.1134/S1070363219020245
- ID: 222764
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
Novel polycyclic compounds, 1-pyrene-based pyridone derivatives, are synthesized by treatment of pyrenyl acetohydtazide with several arylidenemalononitriles and acetylacetone. Intramolecular cyclization furnishes the functionalized substituted pyridine-2-ones with high yields. Structures of the products are elucidated from the spectral data. Tests on antibacterial activity of the products reveal their high antibacterial effect.
Негізгі сөздер
Авторлар туралы
N. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy; Therapeutic Chemistry Department, Pharmaceutical and Drug Industries Division
Хат алмасуға жауапты Автор.
Email: nkhalifa.c@ksu.edu.sa
Сауд Арабиясы, Riyadh, 11451; Giza
M. Haiba
Therapeutic Chemistry Department, Pharmaceutical and Drug Industries Division
Email: nkhalifa.c@ksu.edu.sa
Египет, Giza
M. Taha
Department of Chemistry, Faculty of Science
Email: nkhalifa.c@ksu.edu.sa
Египет, Menoufia
M. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy
Email: nkhalifa.c@ksu.edu.sa
Сауд Арабиясы, Riyadh, 11451
Қосымша файлдар
