电邮这篇文章 Synthesis and Antibacterial Assay of Some New Pyrenyl Pyridine Candidates
- 作者: Khalifa N.M.1,2, Haiba M.E.2, Taha M.M.3, Al-Omar M.A.1
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隶属关系:
- Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy
- Therapeutic Chemistry Department, Pharmaceutical and Drug Industries Division
- Department of Chemistry, Faculty of Science
- 期: 卷 89, 编号 2 (2019)
- 页面: 319-323
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222764
- DOI: https://doi.org/10.1134/S1070363219020245
- ID: 222764
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详细
Novel polycyclic compounds, 1-pyrene-based pyridone derivatives, are synthesized by treatment of pyrenyl acetohydtazide with several arylidenemalononitriles and acetylacetone. Intramolecular cyclization furnishes the functionalized substituted pyridine-2-ones with high yields. Structures of the products are elucidated from the spectral data. Tests on antibacterial activity of the products reveal their high antibacterial effect.
作者简介
N. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy; Therapeutic Chemistry Department, Pharmaceutical and Drug Industries Division
编辑信件的主要联系方式.
Email: nkhalifa.c@ksu.edu.sa
沙特阿拉伯, Riyadh, 11451; Giza
M. Haiba
Therapeutic Chemistry Department, Pharmaceutical and Drug Industries Division
Email: nkhalifa.c@ksu.edu.sa
埃及, Giza
M. Taha
Department of Chemistry, Faculty of Science
Email: nkhalifa.c@ksu.edu.sa
埃及, Menoufia
M. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy
Email: nkhalifa.c@ksu.edu.sa
沙特阿拉伯, Riyadh, 11451
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