Email this article Design, Synthesis and Anticancer Evaluation of Novel Furan Sulphonamide Derivatives
- Authors: Purna Chander Rao G.1, Ramesh V.1, Ramachandran D.1, Kalyan Chakravarthy A.2
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Affiliations:
- Department of Chemistry
- Integrated Product Development
- Issue: Vol 89, No 3 (2019)
- Pages: 486-491
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222798
- DOI: https://doi.org/10.1134/S1070363219030204
- ID: 222798
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Abstract
A series of novel furan sulphonamide derivatives 13a–13j was synthesized. The structures of the compounds are confirmed by 1H and 13C NMR, and mass spectra. All newly synthesized compounds were evaluated for their anticancer activity against three human cancer cell lines, including breast cancer cell (MCF-7), lung cancer cell (A549) and melanoma cancer cell (A-375). The compounds 13a–13c, 13e, 13g–13j demonstrated the activity higher than the positive control.
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About the authors
G. Purna Chander Rao
Department of Chemistry
Author for correspondence.
Email: purnachanderraogudipati1@gmail.com
India, Guntur, Andhra Pradesh
V. Ramesh
Department of Chemistry
Email: purnachanderraogudipati1@gmail.com
India, Guntur, Andhra Pradesh
D. Ramachandran
Department of Chemistry
Email: purnachanderraogudipati1@gmail.com
India, Guntur, Andhra Pradesh
A. Kalyan Chakravarthy
Integrated Product Development
Email: purnachanderraogudipati1@gmail.com
India, Bachupally, Hyderabad
