Design, Synthesis and Anticancer Evaluation of Novel Furan Sulphonamide Derivatives
- Авторлар: Purna Chander Rao G.1, Ramesh V.1, Ramachandran D.1, Kalyan Chakravarthy A.2
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Мекемелер:
- Department of Chemistry
- Integrated Product Development
- Шығарылым: Том 89, № 3 (2019)
- Беттер: 486-491
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222798
- DOI: https://doi.org/10.1134/S1070363219030204
- ID: 222798
Дәйексөз келтіру
Аннотация
A series of novel furan sulphonamide derivatives 13a–13j was synthesized. The structures of the compounds are confirmed by 1H and 13C NMR, and mass spectra. All newly synthesized compounds were evaluated for their anticancer activity against three human cancer cell lines, including breast cancer cell (MCF-7), lung cancer cell (A549) and melanoma cancer cell (A-375). The compounds 13a–13c, 13e, 13g–13j demonstrated the activity higher than the positive control.
Негізгі сөздер
Авторлар туралы
G. Purna Chander Rao
Department of Chemistry
Хат алмасуға жауапты Автор.
Email: purnachanderraogudipati1@gmail.com
Үндістан, Guntur, Andhra Pradesh
V. Ramesh
Department of Chemistry
Email: purnachanderraogudipati1@gmail.com
Үндістан, Guntur, Andhra Pradesh
D. Ramachandran
Department of Chemistry
Email: purnachanderraogudipati1@gmail.com
Үндістан, Guntur, Andhra Pradesh
A. Kalyan Chakravarthy
Integrated Product Development
Email: purnachanderraogudipati1@gmail.com
Үндістан, Bachupally, Hyderabad
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