Email this article Synthesis and Investigation of Copper Complexes with Selected Azomethine Monobenzo Crown Ether Derivatives
- Authors: Sadovskaya N.Y.1, Glushko V.N.1, Baryshnikova M.A.1, Afanasyeva D.A.1, Zhila M.Y.1, Belus S.K.1
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Affiliations:
- The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”
- Issue: Vol 89, No 3 (2019)
- Pages: 440-445
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222787
- DOI: https://doi.org/10.1134/S1070363219030125
- ID: 222787
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Abstract
A series of novel azomethine derivatives of benzo-18-crown-6, benzo-15-crown-5, and aniline as well as their complexes with copper(II) acetate have been synthesized. Using the MTT assay, the antitumor activity of the obtained compounds has been determined. The effect of individual structural elements on the antitumor activity of the whole compound has been assessed.
About the authors
N. Yu. Sadovskaya
The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”
Email: tetrazoli@yandex.ru
Russian Federation, Bogorodskii Val 3, Moscow, 107076
V. N. Glushko
The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”
Author for correspondence.
Email: tetrazoli@yandex.ru
Russian Federation, Bogorodskii Val 3, Moscow, 107076
M. A. Baryshnikova
The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”
Email: tetrazoli@yandex.ru
Russian Federation, Bogorodskii Val 3, Moscow, 107076
D. A. Afanasyeva
The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”
Email: tetrazoli@yandex.ru
Russian Federation, Bogorodskii Val 3, Moscow, 107076
M. Yu. Zhila
The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”
Email: tetrazoli@yandex.ru
Russian Federation, Bogorodskii Val 3, Moscow, 107076
S. K. Belus
The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”
Email: tetrazoli@yandex.ru
Russian Federation, Bogorodskii Val 3, Moscow, 107076
