Synthesis and Investigation of Copper Complexes with Selected Azomethine Monobenzo Crown Ether Derivatives


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Resumo

A series of novel azomethine derivatives of benzo-18-crown-6, benzo-15-crown-5, and aniline as well as their complexes with copper(II) acetate have been synthesized. Using the MTT assay, the antitumor activity of the obtained compounds has been determined. The effect of individual structural elements on the antitumor activity of the whole compound has been assessed.

Sobre autores

N. Sadovskaya

The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”

Email: tetrazoli@yandex.ru
Rússia, Bogorodskii Val 3, Moscow, 107076

V. Glushko

The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”

Autor responsável pela correspondência
Email: tetrazoli@yandex.ru
Rússia, Bogorodskii Val 3, Moscow, 107076

M. Baryshnikova

The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”

Email: tetrazoli@yandex.ru
Rússia, Bogorodskii Val 3, Moscow, 107076

D. Afanasyeva

The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”

Email: tetrazoli@yandex.ru
Rússia, Bogorodskii Val 3, Moscow, 107076

M. Zhila

The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”

Email: tetrazoli@yandex.ru
Rússia, Bogorodskii Val 3, Moscow, 107076

S. Belus

The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”

Email: tetrazoli@yandex.ru
Rússia, Bogorodskii Val 3, Moscow, 107076


Declaração de direitos autorais © Pleiades Publishing, Ltd., 2019

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