Synthesis and Investigation of Copper Complexes with Selected Azomethine Monobenzo Crown Ether Derivatives


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Аннотация

A series of novel azomethine derivatives of benzo-18-crown-6, benzo-15-crown-5, and aniline as well as their complexes with copper(II) acetate have been synthesized. Using the MTT assay, the antitumor activity of the obtained compounds has been determined. The effect of individual structural elements on the antitumor activity of the whole compound has been assessed.

Об авторах

N. Sadovskaya

The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”

Email: tetrazoli@yandex.ru
Россия, Bogorodskii Val 3, Moscow, 107076

V. Glushko

The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”

Автор, ответственный за переписку.
Email: tetrazoli@yandex.ru
Россия, Bogorodskii Val 3, Moscow, 107076

M. Baryshnikova

The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”

Email: tetrazoli@yandex.ru
Россия, Bogorodskii Val 3, Moscow, 107076

D. Afanasyeva

The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”

Email: tetrazoli@yandex.ru
Россия, Bogorodskii Val 3, Moscow, 107076

M. Zhila

The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”

Email: tetrazoli@yandex.ru
Россия, Bogorodskii Val 3, Moscow, 107076

S. Belus

The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances of National Research Centre “Kurchatov Institute”

Email: tetrazoli@yandex.ru
Россия, Bogorodskii Val 3, Moscow, 107076


© Pleiades Publishing, Ltd., 2019

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