Email this article Microwave-Assisted Synthesis of Novel Spirochromanone–Aurone Hybrids and Their Antimicrobial Activity
- Authors: Ramana Kishore N.1, Ashok D.2, Sarasija M.3, Murthy N.Y.3
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Affiliations:
- Vishnu Chemicals Ltd.
- Green and Medicinal Chemistry Laboratory, Department of Chemistry
- Department of Chemistry
- Issue: Vol 88, No 5 (2018)
- Pages: 1015-1019
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222209
- DOI: https://doi.org/10.1134/S1070363218050298
- ID: 222209
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Abstract
New chromanone and aurone hybrids have been synthesized by conventional and microwave induced methods from substituted (E)-7-hydroxy-6-[3-(p-tolyl)acryloyl]spiro[chroman-2,1'-cyclohexan]-4-one with high yields. Structures of the synthesized compounds have been elucidated from IR, 1H and 13C NMR, and mass spectra. All newly synthesized compounds were tested in vitro for their antimicrobial activity. Methoxysubstituted spirochromanones revealed the best antimicrobial profile.
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About the authors
N. Ramana Kishore
Vishnu Chemicals Ltd.
Email: ashokdou@gmail.com
India, Jeedimetla, Hyderabad, Telangana, 500055
D. Ashok
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Author for correspondence.
Email: ashokdou@gmail.com
India, Hyderabad, Telangana, 500007
M. Sarasija
Department of Chemistry
Email: ashokdou@gmail.com
India, Karimnagar, 505002
N. Y. S. Murthy
Department of Chemistry
Email: ashokdou@gmail.com
India, Hyderabad, Telangana, 500088
