Enviar artigo por via de e-mail Microwave-Assisted Synthesis of Novel Spirochromanone–Aurone Hybrids and Their Antimicrobial Activity
- Autores: Ramana Kishore N.1, Ashok D.2, Sarasija M.3, Murthy N.3
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Afiliações:
- Vishnu Chemicals Ltd.
- Green and Medicinal Chemistry Laboratory, Department of Chemistry
- Department of Chemistry
- Edição: Volume 88, Nº 5 (2018)
- Páginas: 1015-1019
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222209
- DOI: https://doi.org/10.1134/S1070363218050298
- ID: 222209
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Resumo
New chromanone and aurone hybrids have been synthesized by conventional and microwave induced methods from substituted (E)-7-hydroxy-6-[3-(p-tolyl)acryloyl]spiro[chroman-2,1'-cyclohexan]-4-one with high yields. Structures of the synthesized compounds have been elucidated from IR, 1H and 13C NMR, and mass spectra. All newly synthesized compounds were tested in vitro for their antimicrobial activity. Methoxysubstituted spirochromanones revealed the best antimicrobial profile.
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Sobre autores
N. Ramana Kishore
Vishnu Chemicals Ltd.
Email: ashokdou@gmail.com
Índia, Jeedimetla, Hyderabad, Telangana, 500055
D. Ashok
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Autor responsável pela correspondência
Email: ashokdou@gmail.com
Índia, Hyderabad, Telangana, 500007
M. Sarasija
Department of Chemistry
Email: ashokdou@gmail.com
Índia, Karimnagar, 505002
N. Murthy
Department of Chemistry
Email: ashokdou@gmail.com
Índia, Hyderabad, Telangana, 500088
